In the new film “Charlize Theron. But the film honors an enduring legacy of movies where two characters film themselves drawn to one another despite disparate goals, points of view, personalities or lifestyles. To commemorate the film , we’ve assembled a shortlist of notable odd-couple pairings that have changed and inspired the way we look at relationships on the silver screen and in our daily lives.

“Jack Lemmon fends off (and eventually kinda-sorta succumbs to) the advances of a millionaire too blinded by love to care that he isn’t a she.

“Katharine Ross).

“Ruth Gordon) who teaches him to forget about his obsession with death and just enjoy life.

"Daryl Hannah) who reunite as adults after falling in love as children. The culture-shock jokes for the former bottom-dweller prove less affecting than the tender romance that blossoms between the two despite a scientist’s (Eugene Levy) determination to uncover her true identity.

"Lea Thompson).

"Rick Rossovitch).

"Who Framed Roger Rabbit" (1988) - You won’t see a more devoted pair than goofball rabbit Roger (Charles Fleischer) and his hourglass-shaped spouse Jessica (Kathleen Turner), whose marriage is tested when Roger becomes a murder suspect.

"Winona Ryder) and the weaponized hands that come between them.

"The Professional" (1994) - Luc Besson wrote and directed this film about a hit man (Gary Oldman) trying to cover up the trail of his corruption.

"Helen Hunt), resulting in love and some important life lessons for both of them.

"Emily Watson) without any siblings, finding the perfect balance together.

"James Spader) who quite literally whips her into shape.

"Naomi Watts) comes to care deeply for Kong (Andy Serkis) as he slowly changes from her captor to her protector.

"Ryan Gosling stars in this unusual story about a socially-awkward young man who finds an unlikely but perfect companion in a life-size female doll he orders from an adult website.

"Rooney Mara).

"Teresa Palmer) who quite literally teaches him how to live again.